Consult with a physician, but most medications can be taken while on naltrexone. It’s important to let the doctor know what medications are being taken prior to naltrexone therapy so that any contraindications can be determined. Naltrexone will block the effect of opioid pain relievers so it is important to notify medical personnel if you are receiving naltrexone treatment. It may also render cough and cold medications containing opioids ineffective. During naltrexone therapy, program participants carry a medical card that may be carried discreetly in one’s wallet or purse. In the event of that someone on naltrexone therapy requires pain relief due to any medical circumstances, alternative analgesia or high doses of opioid medication may be administered in the monitored hospital setting. There are a number of readily available alternative pain relievers that can be used in conjunction with naltrexone. Acetaminophen, aspirin, ibuprofen, naproxen, gabapentin, lidocaine patches, muscle relaxers, steroids, and various other alternative pain relief and anti-inflammatory medications may be effectively used while on naltrexone therapy. In addition, the implant can be removed and narcotics administered after naltrexone is out of the patient’s system. This can take several hours or days.